FeelTheDifference

Now, get trusted antibiotics in a soft, conforming biomatrix envelope.

Trusted
Antibiotics

Soft
Conforming Feel

Proven
Biomatrix

The soft, conforming EluPro BioEnvelope is designed to

Provide antibiotic protection at the implant site for an extended period post-implant.
Prevent post-operative complications for devices such as pacemakers and defibrillators.
Regenerate into healthy vascularized tissue.^1-4

Feel

the difference biology makes

Visit us at Heart Rhythm 2025
April 25^th – 27^th
Booth# 2418

The benefits of Elutia’s BioEnvelopes

The natural base material (biologic extracellular matrix, or ECM) in all Elutia BioEnvelopes improves biocompatibility between the device and patient by supporting healthy tissue formation and a regenerative healing response.^1-4

EluPro includes the trusted antibiotics rifampin and minocycline that have been shown to reduce bacterial colonization in a preclinical model.⁵

Soft feel and natural lubricity when hydrated, to conform to the shape of the CIED for a better implant experience^2,3 and provide both acute and long-term device stability.^4,6

Support the regeneration of healthy, vascularized tissue^2-4 pocket (versus fibrotic, calcified tissue⁷), mitigating a long-term foreign body response.

“When an Elutia BioEnvelope was used at initial CIED implantation (vs no envelope), we observed significantly less fibrous lead entrapment, easier generator and lead mobilization, and thinner mature fibrotic capsules at reoperation. Biologic tissue envelopes may prevent operative complications and enhance clinical outcomes.”

John Catanzaro, MD, MBA

1. Piterina AV, et al. Int J Mol Sci. 2009 Nov 20;10(10):4375-417.
2. Catanzaro JN, et al. Circulation. 2022; 146: A11052.
3. Catanzaro JN, et al. Heart Rhythm. 2023;20(5): S712-S713.
4. Deegan, et al. J Regen Med. 2022;11:5.
5. Garrigos ZE, et al. Front. Drug Deliv. 2024;4:1441956.
6. CanGaroo Envelope Instructions for Use
7. Badylak S, et al. Semin Immunol. 2008 Apr;20(2):109-16.

WMK-1856-01A