Designed to Support New Bone Growth in Spine and Orthopedic Surgical Procedures.1
OsteGro Bone Matrices
OsteGro Allograft Bone Matrix, the second product in this family, is a sterile bone matrix comprised of cancellous particles and demineralized cortical fibers.
The Elutia Advantage
Elutia has developed a proprietary processing methodology for human tissue that creates VBM allografts that contain the scaffold, growth factors and cells required for regeneration. Elutia has designed the process to protect native elements of bone, including growth factors and osteoprogenitor cells that are known to be biologically active and critical for successful bone formation.2
Bone Regeneration Elements Preserved.
The 3 Essential Elements
Osteogenesis
Cells capable of differentiating to bone cell lineage and synthesizing bone matrices.
Osteoinductivity
Bioactive growth factors capable of inducing osteoblast differentiation, growth and maturation.
Osteoconductivity
Scaffolds cued as substrate for supporting cellular activities and bone matrix organization.
Optimized Cellular Health to Improve Osteogenesis.
Typical VBM tissue processes may include steps that can increase apoptosis (cell death) and reduce osteogenic potential.3,4,5 Elutia’s proprietary gentle VBM process minimizes damaged, apoptotic (dying) cells resulting in VBMs that proliferate faster than competitive products, which is associated with greater osteogenic potential.2
Industry standard methods for cell counting cannot distinguish between living and dying (apoptotic) cells in the final product, leading to overestimates in the viable cell content of bone matrices. Elutia has developed a measurement system which can demonstrate the reduction in apoptotic cell content of its products.2
Substantially Fewer Apoptotic Cells 2
Faster Rate of Cell Proliferation vs. Control1
Optimized Osteoinductivity.
Demonstrated osteoinductivity based on Elutia’s proprietary demineralization process.2
Bioactivity: Elutia VBM Demonstrates Osteoinductivity in Vivo
Elutia Process Yields Higher BMP-2 and BMP-7 Levels Than a Control2
Elutia’s proprietary processing also addresses the need for optimizing the osteoinductivity of cellular bone matrices. Processing parameters are designed to maximize availability of the natural growth factors in bone resulting in bone formation.1
Photo: Cancellous bone matrix for illustration purposes only.
Naturally Osteoconductive.
Elutia’s proprietary VBM processing produces a natural 3-dimensional scaffold for bone formation (conduction) at the implant site.2
Optimized Handling.
Unique handling properties support ease of placement at implant site.
Shape
Form
Mold
Implant
Product Specifications
Inter-operative Ease of Use
- No decanting decreases prep and thaw time
- Thaws in 5-15 minutes*
- No rinsing prior to implantation
* dependent on allograft volume
Sizing and Ordering Information
Product Numbers are for U.S. only.
OsteGro V Osteo Viable Bone Matrix is offered frozen in 1cc, 2cc, 5cc and 10cc vials and, once thawed, requires no additional steps for implantation.
| wdt_ID | Product Number | Name | Size |
|---|---|---|---|
| 1 | OSGV-0001 | OsteGro V Osteo Viable Matrix | 1cc |
| 2 | OSGV-0002 | OsteGro V Osteo Viable Matrix | 2cc |
| 3 | OSGV-0005 | OsteGro V Osteo Viable Matrix | 5cc |
| 4 | OSGV-0010 | OsteGro V Osteo Viable Matrix | 10cc |
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IFU for U.S. only.
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1. Elutia Biologics Data on File
2. Eder et al. Eur Spine J. 2011. 20.
3. Li et al. J Orthopaedic Res. 1999. 17 (6).
4. Dolan et al. J. R. Soc Interface. 2012. 9.