![ViBone Viable Bone Matrix Product Logo Aziyo ViBone Product Logo](https://Aziyobiologstg.wpengine.com/wp-content/uploads/2020/06/ViBone_Product-Page_White-Logo-1.png)
![](https://Aziyobiologstg.wpengine.com/wp-content/uploads/2020/05/Aziyo-Curved-BG-Five-1.png)
Next Generation Viable Bone Matrix, Closer to High-Quality Autograft.1
ViBone Viable Bone Matrix (VBM)
ViBone is comprised of cancellous bone particles with preserved cells and demineralized cortical bone particles produced via Elutia’s gentle proprietary VBM process.
The Aziyo Advantage
Elutia has developed a proprietary processing methodology for human tissue that creates VBM allografts that contain the scaffold, growth factors and cells required for regeneration. Elutia has designed the process to protect native elements of bone, including growth factors and osteoprogenitor cells that are known to be biologically active and critical for successful bone formation.2
![ViBone Viable Bone Matrix Product Image Person with green gloves stretching ViBone](https://Aziyobiologstg.wpengine.com/wp-content/uploads/2020/06/ViBone-Image.jpg)
Bone Regeneration Elements Preserved.
The 3 Essential Elements
![Aziyo Bone Regeneration Diagram Diagram outlining the main elements of bone regeneration](https://Aziyobiologstg.wpengine.com/wp-content/uploads/2020/06/Aziyo_Bone-Regeneration-Diagram-2.png)
Osteogenesis
Cells capable of differentiating to bone cell lineage and synthesizing bone matrices.
Osteoinductivity
Bioactive growth factors capable of inducing osteoblast differentiation, growth and maturation.
Osteoconductivity
Scaffolds cued as substrate for supporting cellular activities and bone matrix organization.
![Viable Bone Matrix Patient Image Person sitting on the ground tying their shoe](https://Aziyobiologstg.wpengine.com/wp-content/uploads/2020/06/Aziyo_Interior_VBM-Patient-Image.png)
Optimized Cellular Health to Improve Osteogenesis.
Typical VBM tissue processes may include steps that can increase apoptosis (cell death) and reduce osteogenic potential.3,4,5 Elutia’s proprietary gentle VBM process minimizes damaged, apoptotic (dying) cells resulting in VBMs that proliferate faster than competitive products, which is associated with greater osteogenic potential.2
Industry standard methods for cell counting cannot distinguish between living and dying (apoptotic) cells in the final product, leading to overestimates in the viable cell content of bone matrices. Elutia has developed a measurement system which can demonstrate the reduction in apoptotic cell content of its products.2
Substantially Fewer Apoptotic Cells 2
![Aziyo Viable Bone Matrix Data Chart chart with arrow and boxes showing that Aziyo ABM has Fewer Apoptotic Cells](https://Aziyobiologstg.wpengine.com/wp-content/uploads/2020/07/Aziyo_VBM-Data_1-V7.jpg)
Faster Rate of Cell Proliferation vs. Control1
![Aziyo Viable Bone Matrix Data Graph A data graph showing a line increasing from left to right](https://Aziyobiologstg.wpengine.com/wp-content/uploads/2020/07/Aziyo_VBM-Data_2-V3.jpg)
Optimized Osteoinductivity.
Demonstrated osteoinductivity based on Aziyo’s proprietary demineralization process.2
Bioactivity: Elutia VBM Demonstrates Osteoinductivity in Vivo
![Aziyo_VBM-Data_3-V2 The body's response to Viable Bone Matrix](https://Aziyobiologstg.wpengine.com/wp-content/uploads/2020/07/Aziyo_VBM-Data_3-V2.jpg)
Elutia Process Yields Higher BMP-2 and BMP-7 Levels Than a Control2
![Aziyo Viable Bone Matrix Data Data Chart with orange boxes and arrows](https://Aziyobiologstg.wpengine.com/wp-content/uploads/2020/07/Aziyo_VBM-Data_4-V5.jpg)
Aziyo’s proprietary processing also addresses the need for optimizing the osteoinductivity of cellular bone matrices. Processing parameters are designed to maximize availability of the natural growth factors in bone resulting in bone formation.1
![OsteGro Viable Bone Matrix close up close up illustration of Cancellous bone matrix](https://Aziyobiologstg.wpengine.com/wp-content/uploads/2020/07/OsteGro_Bone-Image-2.jpg)
Photo: Cancellous bone matrix for illustration purposes only.
Naturally Osteoconductive.
Elutia’s proprietary VBM processing produces a natural 3-dimensional scaffold for bone formation (conduction) at the implant site.2
Optimized Handling.
Unique handling properties support ease of placement at implant site.
![ViBone Viable Bone Matrix Product Image Person holding a round piece of ViBone on a dark blue surface](https://Aziyobiologstg.wpengine.com/wp-content/uploads/2020/06/VBM-Image-Square_Shape.jpg)
Shape
![ViBone Viable Bone Matrix Product Image Person molding ViBone between their fingers](https://Aziyobiologstg.wpengine.com/wp-content/uploads/2020/06/VBM-Image-Square_Form.jpg)
Form
![ViBone Viable Bone Matrix Product Image Person in while gloves molding Vibone](https://Aziyobiologstg.wpengine.com/wp-content/uploads/2020/06/VBM-Image-Square_Mold.jpg)
Mold
![ViBone Viable Bone Matrix Product Image Person holding piece of ViBone that is ready to be implanted](https://Aziyobiologstg.wpengine.com/wp-content/uploads/2020/06/VBM-Image-Square_Implant.jpg)
Implant
Product Specifications
Inter-operative Ease of Use
- No decanting decreases prep and thaw time
- Thaws in 5-15 minutes*
- No rinsing prior to implantation
* dependent on allograft volume
Sizing and Ordering Information
Product Numbers are for U.S. only.
ViBone Viable Bone Matrix is offered frozen in 1cc, 2cc, 5cc and 10cc vials and, once thawed, requires no additional steps for implantation.
wdt_ID | Product Number | Name | Size |
---|---|---|---|
1 | VIB-0001 | ViBone Viable Bone Matrix | 1cc |
2 | VIB-0002 | ViBone Viable Bone Matrix | 2cc |
3 | VIB-0005 | ViBone Viable Bone Matrix | 5cc |
4 | VIB-0010 | ViBone Viable Bone Matrix | 10cc |
Download IFU
IFU for U.S. only.
Interested in ViBone?
Learn About ViBone Today!
To schedule a product demo or request an in-service for a product evaluation contact us today.
1. Based on Apoptosis Data on File
2. Elutia Biologics Data on File
3. Eder et al. Eur Spine J. 2011. 20.
4. Li et al. J Orthopaedic Res. 1999. 17 (6).
5. Dolan et al. J. R. Soc Interface. 2012. 9.